I could start with stars in my eyes about “global collaboration”. I have repeatedly asserted that it is about permanent interests.
I necessarily don’t agree with the broad strokes painted here but global collaboration is important. Science funding is being scaled back in a number of countries and for me, the central point here- a reassessment.
Because Covid-19 doesn’t respect borders, we must improve international scientific collaboration. The solidarity of the global scientific and medical community at the start of this pandemic is the blueprint for the future. Chinese scientists sequenced the genome of the new coronavirus on January 11 and posted it online, enabling German colleagues to develop a screening test, which was then shared by the WHO with governments everywhere.
For example, in cancer “research”
- How much do we need to understand pathways?
- How have they helped to “progress”.
- Why there is no research in fundamental radiobiology? Long term side effects and intermediaries? Radiation is the ONLY modality that actually kills the cancer cells.
- Reassessment of the effect of “biologicals”.
- Reproducible research.
- Global collaboration to pool in efforts to avoid duplication and sharing the spoils with everyone involved. There seems to be a basic mistrust between researchers because there’s a race to determine the “next target” and potentially a new “blockbuster drug”.
- Research in palliative care- that gets the short shrift because of perverted payouts- change that equation and suddenly you’d find that capitalism doesn’t really care about human lives. Let humans die without suffering and not chasing a chimaera of “progression-free-survival”.
- Can we stop gloating about drosphilas and fruit flies?
- Making genomic sequencing more accessible by researching/ramping up production of reagents. I still remain a strong votary of personalised radiation oncology- through specific genomics and bioinformatics. One that has a true potential to underpin mechanisms involved in the genesis of side effects and hopefully reducing them to improve quality of life.